A Unifying Model-Based Hypothesis for the Diverse Waveforms of Infantile Nystagmus Syndrome
نویسندگان
چکیده
L.F. Dell’Osso, Ph.D., Professor Emeritus of Neurology Daroff-Dell’Osso Ocular Motility Laboratory Louis Stokes Cleveland Veterans Affairs Medical Center 10701 East Boulevard, Cleveland, OH 44106 USA Telephone: (216) 421-3224—FAX: (216) 231-3461 E-mail: [email protected]—Web Site: www.omlab.org forms, where the jerk slow phases are usually increasing velocity (or “runaway”) exponentials. These accelerating slow phases are always towards the neutral zone (Dell'Osso & Daroff, 1975; Dell'Osso, Flynn, & Daroff, 1974). The primary subsystem instability in INS is hypothesized to lie in the normally underdamped smooth pursuit system; vestibular dysfunction (imbalance) may also be present and would account for the less-prevalent linear waveforms seen in some patients. In individuals demonstrating an additional high-frequency sinusoidal oscillation (producing dual jerk waveforms), the A Unifying Model-Based Hypothesis for the Diverse Waveforms of Infantile Nystagmus Syndrome
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